进化遗传与动物模型全国重点实验室研究员，博士生导师。国家自然科学基金委青年基金A类项目（原国家杰青）、B类项目（原国家优青）获得者，云南省“万人计划”青年拔尖人才、中国科学院“青年创新促进会”会员。主要以非模式动物为研究对象，结合比较基因组学、进化遗传学和功能基因组学的理论和方法，探讨适应性复杂性状起源和演化的分子遗传机制。以通讯作者在Science, Nature Communications, PNAS, Molecular Biology and Evolution等国际著名期刊发表数十篇研究论文。先后承担了国家自然科学基金青年基金、面上项目、重点项目等。

学习和工作经历

2018.09 – 至今：中国科学院昆明动物研究所，遗传进化与动物模型全国重点实验室，研究员

2013.01 – 2018.09：中国科学院昆明动物研究所，遗传资源与进化国家重点实验室，副研究员

2016.12 – 2017.12：密歇根大学，生态与进化生物学系，访问学者

2007.09 – 2013.01：中国科学院昆明动物研究所，获博士学位

2002.09 – 2006.06：烟台大学，生命科学学院，获学士学位

近5年内发表的代表性论文/专著

1. Lyu X.^#, Bai J.^#, Jiang, J.-B.^#, Sun C.-J., Chen P., Liu Q., Ma Y.-S., Liu Z^*. (2025). Single-cell expression profiling of bat wing development. Nature Communications. 16(1): 6612.

2. Guo Y.-T.^#, Jiang J.-B.^#, Qiao G.-R.^#, Luo R.-H., Zhou X., Hua R., Zheng C.-B.^*, & Liu Z^* (2024) Pleiotropy of positive selection in ancient ACE2 suggests an alternative hypothesis for bat-specific adaptations to host coronaviruses. PNAS 121: e2321619121.

3. Hua R.^#, Ma Y.-S.^#, Yang L.^#, Hao J.-J., Hua Q.-Y., Shi L.-Y., Yao X.-Q., Zhi H.-Y. & Liu Z^* (2024) Experimental evidence for cancer resistance in a bat species. Nature Communications, 15: 1401.

4. He K^#, Liu Q^#, Xu DM^#, Qi FY^#, Bai J, He SW, Chen P, Zhou X, Cai WZ, Chen ZZ, Liu Z^*, Jiang XL^*, Shi P^* (2021) Echolocation in soft-furred tree mice. Science 372: eaay1513.

5. Hao J.-J., Hao W.-L., Liu Z^*, Shi P^* (2022) The toggle switch model for gene expression change during the prenatal-to-postnatal transition in mammals. Molecular Biology and Evolution. 36: msac036.

其他代表性论文/专著

1. Ren Y.-Y., Liu Z*. (2024) Characterization of single-cell cis-regulatory elements informs implications for cell differentiation. Genome Biology and Evolution. 16:evae241.

2. Liu Z, Qi FY, Xu DM, Zhou X, Shi P^* (2018) Genomic and functional evidence reveals molecular insights into the origin of echolocation in whales. Science Advances. 4:eaat8821.

3. Li YY^#, Liu Z^#*, Qi FY, Zhou X, Shi P^* (2016) Functional effects of a retained ancestral polymorphism in prestin. Molecular Biology and Evolution 34:88-92.

4. Liu Z, Qi FY, Zhou X, Ren HQ, Shi P^* (2014) Parallel sites implicate functional convergence of the hearing gene prestin among echolocating mammals. Molecular Biology and Evolution 31:2415-2424.

5. Liu Z^* (2014) Codon 104 of p53 is not an adaptively selected site for extreme environments in mammals of the Tibet plateau. PNAS 111:E2357.