刘书，研究员，博士生导师。长期从事脑影像与多组学数据整合分析研究，综合运用遗传学、神经影像学和计算统计学等多学科手段，揭示脑个体差异规律及其生物学机制。在Nature Human Behaviour、Nature Mental Health、Advanced Science和 British Journal of Psychiatry等期刊发表论文10余篇。

经历

2012.09 - 2016.07  哈尔滨工程大学，信息安全专业，学士

2016.09 - 2019.07  中国科学院自动化研究所，模式识别与智能系统，硕士

2019.09 - 2024.01  荷兰阿姆斯特丹大学，神经科学，博士

2024.04 - 至今     中国科学院昆明动物研究所，方向负责人

方向一

人类复杂性状的影像组学研究。基于神经影像和多组学数据，利用人工智能算法，识别与复杂疾病和认知行为相关的大脑生物标记物，探索基因-大脑-表型的通路机制。 

方向二

猕猴脑影像组学与跨物种比较研究。开展猕猴脑影像组学整合分析，系统解析猕猴大脑个体差异的规律，并与人类进行跨物种比较研究，揭示人与猕猴在脑结构、功能个体差异及分子机制上的共性与特异性。

近5年内发表的代表性论文/专著

1. Shu Liu*; Abdel Abdellaoui; Karin JH Verweij; Guido A van Wingen*; Replicable brain–

phenotype associations require large-scale neuroimaging data, Nature Human Behaviour, 2023, 7(8):1344-1356

2. Shu Liu*; Abdel Abdellaoui; Guido A van Wingen；Karin JH Verweij*; The relation

between cortical gene expression and the neural correlates of risky behavior, Nature Mental

Health, 2024, 2(10): 1183-1195

3. Shu Liu*; Abdel Abdellaoui; Karin J. H. Verweij; Guido A. van Wingen*; Gene Expression hasDistinct Associations with Brain Structure and Function in Major Depressive Disorder, Advanced Science, 2023, 10(7): 2205486

4. Shu Liu*; Dirk J A Smit; Abdel Abdellaoui; Guido A van Wingen; Karin J H Verweij*; Brain

structure and function show distinct relations with genetic predispositions to mental health and cognition, Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 2023, 8(3): 300-310

5. Shu Liu; Ang Li; Yong Liu; Hao Yan; Meng Wang; Yuqing Sun; Lingzhong Fan; Ming Song;

Kaibin Xu; Jun Chen; Yunchun Chen; Huaning Wang; Hua Guo; Ping Wan; Luxian Lv; Yongfeng Yang; Peng Li; Lin Lu; Jun Yan; Huiling Wang; Hongxing Zhang; Huawang Wu; Yuping Ning; Dai Zhang; Tianzi Jiang; Bing Liu*; Polygenic effects of schizophrenia on hippocampal grey matter volume and hippocampus-medial prefrontal cortex functional connectivity, British Journal of Psychiatry,2020, 216(5): 267-274

其他代表性论文/专著

1. Shu Liu; Ang Li; Yong Liu; Jin Li; Meng Wang; Yuqing Sun; Wen Qin; Chunshui Yu; Tianzi

Jiang; Bing Liu*; MIR137 polygenic risk is associated with schizophrenia and affects functional connectivity of the dorsolateral prefrontal cortex, Psychological Medicine, 2020, 50(9): 1510-1518

2. Shu Liu; Ang Li; Meifang Zhu; Jin Li; Bing Liu*; Genetic influences on cortical

myelination in the human brain, Genes, Brain and Behavior, 2019, 18(4): e12537

3. Ang Li; Andrew Zalesky; Weihua Yue; Oliver D. Howes; Hao Yan; Yong Liu; Lingzhong Fan;

Kirstie Whitaker; Kaibin Xu; Guangxiang Rao; Jianjun Li; Shu Liu; Meng Wang; Yuqing Sun; Ming Song; Peng Li; Jun Chen; Yunchun Chen; Huaning Wang; Wenming Liu; Zhigang Li; Yongfeng Yang; Hua Guo; Ping Wan; Luxian Lv; Lin Lu; Jun Yan; Yuqing Song; Huiling Wang; Hongxing Zhang; Huawang Wu; Yuping Ning; Yuhui Du; Yuqi Cheng; Jian Xu; Xiufeng Xu; Dai Zhang; Xiaoqun Wang; Tianzi Jiang; Bing Liu*; A neuroimaging biomarker for striatal dysfunction in schizophrenia, Nature Medicine,2020, 26(4): 558-565

4. Yanhui Ding; Kun Zhao; Tongtong Che; Kai Du; Hongzan Sun; Shu Liu; Yuanjie Zheng; Shuyu

Li; Bing Liu; Yong Liu ; Quantitative Radiomic Features as New Biomarkers for Alzheimer’s Disease: An Amyloid PET Study, Cerebral Cortex, 2021, 31(8): 3950-3961

5. Yongfeng Yang; Shu Liu; Xiaoyan Jiang; Hongyan Yu; Shuang Ding; Yanli Lu; Wenqiang Li;

Hongxing Zhang; Bing Liu; Yue Cui; Lingzhong Fan; Tianzi Jiang; Luxian Lv ; Common and Specific Functional Activity Features in Schizophrenia, Major Depressive Disorder, and Bipolar Disorder,Frontiers in Psychiatry, 2019, 10: 428719