简历

和耀喜，中国科学院昆明动物研究所，研究员，博士生导师。中国科学院青年创新促进会会员，中国科学院特聘研究骨干，云南省“兴滇英才支持计划”青年人才。

研究方向和兴趣

主要聚焦人类基因组多样性与环境适应的遗传学机研究。目前，以第一作者和通讯作者（含共同）的身份在Nature、Nature Communications、National Science Review、Current Biology、Molecular Biology and Evolution等国际著名学术期刊上发表论文20余篇。曾获中国科学院院长优秀奖，云南省优秀博士学位论文等。目前主持国自然青年B类、C类以及面上项目、云南省基础研究计划优秀青年项目、担任国家重点研发计划课题负责人，中国科学院“十四五”院级特聘骨干，云南省“兴滇英才”支持计划青年人才，2020年入选中国科学院青年创新促进会。

学习和工作经历 

2024-01至今      中国科学院昆明动物研究所, 比较基因组实验室, 研究员

2019-09至2023-12 中国科学院昆明动物研究所, 比较基因组实验室, 副研究员 

2019-07至2019-08  中国科学院昆明动物研究所, 比较基因组实验室, 助理研究员 

2014-09至2019-06  中国科学院大学, 遗传学博士, 导师: 宿兵 

2010-09至2014-07  云南大学, 生物科学（国家生物学基地班）, 理学学士 

1.  He Yaoxi, Zhang Xiaoming, Peng Min-Shen, Li Yu-Chun, Liu Kai, Zhang Yu, Mao Leyan, Guo Yongbo, Ma Yujie, Zhou Bin, Zheng Wangshan, Yue Tian, Liao Yuwen, Liang Shen-Ao, Chen Lu, Zhang Weijie, Chen Xiaoning, Tang Bixia, Yang Xiaofei, Ye Kai, Gao Shenhan, Lu Yurun, Wang Yong, Wan Shijie, Hao Rushan, Wang Xuankai, Mao Yafei, Dai Shanshan, Gao Zonglian, Yang Li-Qi, Guo Jianxin, Li Jiangguo, Liu Chao, Wang Jianhua, Sovannary Tuot, Bunnath Long, Kampuansai Jatupol, Inta Angkhana, Srikummool Metawee, Kutanan Wibhu, Ho Quang Huy, Pham Dang Khoa, Singthong Sommay, Sochampa Somphad, Kyaing U. Win, Pongamornkul Wittaya, Morlaeku Chutima, Rattanakrajangsri Kittisak, Consortium of Anthropological Research in Southeast Asia and Southwest China (CASEAC), Kong Qing-Peng, Zhang Ya-Ping, Su Bing. Genome diversity and signatures of natural selection in mainland Southeast Asia. Nature, 2025, 643(8071):417-426.

2.  He Yaoxi; Luo Xin; Zhou Bin; Hu Ting; Meng Xiaoyu; Audano Peter A; Kronenberg Zev N; Eichler Evan E; Jin Jie; Guo Yongbo; Yang Yanan; Qi Xuebin; Su Bing; Long-read assembly of the Chinese rhesus macaque genome and identification of ape-specific structural variants, Nature Communications, 2019, 10: 4233.

3.  He Yaoxi; Qi Xuebin; Ouzhuluobu; Liu Shiming; Li Jun; Zhang Hui; Baimakangzhuo; Bai Caijuan; Zheng Wangshan; Guo Yongbo; Duojizhuoma; Baimayangji; Dejiquzong; Bianba; Gonggalanzi; Pan Yongyue; Qula; Kangmin; Cirenyangji; Guo Wei; Yangla; Peng Yi; Zhang Xiaoming; Xiang Kun; Yang Zhaohui; Wang Liangbang; Gengdeng; Zhang Yanfeng; Wu Tianyi; Su Bing; Cui Chaoying; Blunted nitric oxide regulation in Tibetans under high-altitude hypoxia, National Science Review, 2018, 5(4): 516-529.

4.  He Yaoxi; Guo Yongbo; Zheng Wangshan; Yue Tian; Zhang Hui; Wang Bin; Feng Zhanying; Ouzhuluobu; Cui Chaoying; Liu Kai; Zhou Bin; Zeng Xuerui; Li Liya; Wang Tianyun; Wang Yong; Zhang Chao; Xu Shuhua; Qi Xuebin; Su Bing; Polygenic adaptation leads to a higher reproductive fitness of native Tibetans at high altitude., Current Biology, 2023, 33(19):4037-4051.

5.  He Yaoxi; Zheng Wangshan; Guo Yongbo; Yue Tian; Cui Chaoying; Ouzhuluobu Hui; Zhang Hui; Liu Kai; Yang Zhaohui; Wu Tianyi; Qu Jia; Jin Zi-Bing; Yang Jian; Lu Fan; Qi Xuebin; Su Bing; Deep phenotyping of 11,880 highlanders reveals novel adaptive traits in native Tibetans, iScience, 2023, 26(9): 107677.

6.  He Yaoxi; Li Jun; Yue Tian; Zheng Wangshan; Guo Yongbo; Zhang Hui; Chen Li; Li Chunxia; Li Hongyan; Cui Chaoying; Ouzhuluobu; Qi Xuebin; Su Bing; Seasonality and Sex-Biased Fluctuation of Birth Weight in Tibetan Populations, Phenomics, 2022, 2:64-71.

7.  He Yaoxi; Cui Chaoying; Guo Yongbo; Zheng Wangshan; Yue Tian; Zhang Hui; Ouzhuluobu; Wu Tianyi; Qi Xuebin; Su Bing; High Arterial Oxygen Saturation in the Acclimatized Lowlanders Living at High Altitude. Phenomics, 2023, 3:329–332.

8.  Zheng Wangshan; He Yaoxi; Guo Yongbo; Yue Tian; Zhang Hui; Li Jun; Zhou Bin; Zeng Xuerui; Li Liya; Wang Bin; Cao Jingxin; Chen Li; Li Chunxia; Li Hongyan; Cui Chaoying; Bai Caijuan; Qi Xuebin; Su Bing; Large-scale genome sequencing redefines the genetic footprints of high-altitude adaptation in Tibetans, Genome Biology, 2023, 24(1): 73.

9.  Luo Xin; He Yaoxi; Zhang Chao; He Xiechao; Yan Lanzhen; Li Min; Hu Ting; Hu Yan; Jiang Jin; Meng Xiaoyu; Ji Weizhi; Zhao Xudong; Zheng Ping; Xu Shuhua; Su Bing; Trio deep-sequencing does not reveal unexpected off-target and on-target mutations in Cas9-edited rhesus monkeys, Nature Communications, 2019, 10(1): 5525.

10. Ouzhuluobu; He Yaoxi; Lou Haiyi; Cui Chaoying; Deng Lian; Gao Yang; Zheng Wangshan; Guo Yongbo; Wang Xiaoji; Ning Zhilin; Li Jun; Bai Caijuan; Baimakangzhuo; Gonggalanzi; Dengjiquzong; Bianba; Liu Shiming; Wu Tianyi; Xu Shuhua; Qi Xuebin; Su Bing; De novo assembly of a Tibetan genome and identification of novel structural variants associated with high-altitude adaptation, National Science Review, 2019, 7(2): 391-402.

11. Zhang Xiaoming; Ji Xueping; Li Chunmei; Yang Tingyu; Huang Jiahui; Zhao Yinhui; Wu Yun; Ma Shiwu; Pang Yuhong; Huang Yanyi; He Yaoxi; Su Bing; A Late Pleistocene human genome from Southwest China, Current Biology, 2022, 32(14): 3095

12. Yue Tian, Guo Yongbo, Qi Xuebin, Zheng Wangshan, Zhang Hui, Wang Bin, Liu Kai, Zhou Bin, Zeng Xuerui, Ouzhuluobu, He Yaoxi, Bing Su; Sex-biased regulatory changes in the placenta of native highlanders contribute to adaptive fetal development, eLife, 2024, 13:12:RP89004

13. Zhou Bin; He Yaoxi; Chen Yongjie; Su Bing; Comparative Genomic Analysis Identifies Great-Ape-Specific Structural Variants and Their Evolutionary Relevance, Molecular Biology and Evolution, 2023, 40(8): msad184.